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TRPA1 mediates the hypothermic action of acetaminophen
Acetaminophen (APAP) is an effective antipyretic and one of the most commonly used analgesic drugs. Unlike antipyretic non-steroidal anti-inflammatory drugs, APAP elicits hypothermia in addition to its antipyretic effect. Here we have examined the mechanisms responsible for the hypothermic activity...
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Publicado no: | Sci Rep |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4533162/ https://ncbi.nlm.nih.gov/pubmed/26227887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12771 |
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