Φορτώνει......
Clioquinol and pyrithione activate TRPA1 by increasing intracellular Zn(2+)
The antifungal and amoebicidal drug clioquinol (CQ) was withdrawn from the market when it was linked to an epidemic of subacute myelo-optico-neuropathy (SMON). Clioquinol exerts its anti-parasitic actions by acting as a Cu/Zn chelator and ionophore. Here we show that local injections of CQ produce m...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
National Academy of Sciences
2009
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2688854/ https://ncbi.nlm.nih.gov/pubmed/19416844 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812675106 |
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