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A Simple, High-Yield Synthesis of DNA Duplexes Containing a Covalent, Thermally-Reversible Interstrand Cross-link At a Defined Location()
Interstrand DNA-DNA cross-links are highly toxic to cells because these lesions block the extraction of information from the genetic material. The pathways by which cells repair cross-links are important, but not well understood. The preparation of chemically well-defined cross-linked DNA substrates...
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| Publicado no: | Angew Chem Int Ed Engl |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4532324/ https://ncbi.nlm.nih.gov/pubmed/25967397 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201502566 |
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