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Catalytic Asymmetric Hydroamination of Unactivated Internal Olefins to Aliphatic Amines
Catalytic assembly of enantiopure aliphatic amines from abundant and readily available precursors has long been recognized as a paramount challenge in synthetic chemistry. Herein, we describe a mild and general copper-catalyzed hydroamination that effectively converts unactivated internal olefins, a...
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| Publicado no: | Science |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4532314/ https://ncbi.nlm.nih.gov/pubmed/26138973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aab3753 |
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