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Catalytic Intermolecular Hydroaminations of Unactivated Olefins with Secondary Alkyl Amines

The intermolecular hydroamination of unactivated alkenes with simple dialkyl amines remains an unsolved problem in organic synthesis. Here we report a catalytic protocol for efficient additions of cyclic and acyclic secondary alkyl amines to a wide range of alkyl olefins with complete anti-Markovnik...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Musacchio, Andrew J., Lainhart, Brendan C., Zhang, Xin, Naguib, Saeed G., Sherwood, Trevor C., Knowles, Robert R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5426363/
https://ncbi.nlm.nih.gov/pubmed/28209894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aal3010
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