Islet Oxygen Consumption Rate (OCR) Dose Predicts Insulin Independence in Clinical Islet Autotransplantation

BACKGROUND: Reliable in vitro islet quality assessment assays that can be performed routinely, prospectively, and are able to predict clinical transplant outcomes are needed. In this paper we present data on the utility of an assay based on cellular oxygen consumption rate (OCR) in predicting clinic...

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發表在:PLoS One
Main Authors: Papas, Klearchos K., Bellin, Melena D., Sutherland, David E. R., Suszynski, Thomas M., Kitzmann, Jennifer P., Avgoustiniatos, Efstathios S., Gruessner, Angelika C., Mueller, Kathryn R., Beilman, Gregory J., Balamurugan, Appakalai N., Loganathan, Gopalakrishnan, Colton, Clark K., Koulmanda, Maria, Weir, Gordon C., Wilhelm, Josh J., Qian, Dajun, Niland, Joyce C., Hering, Bernhard J.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2015
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4530873/
https://ncbi.nlm.nih.gov/pubmed/26258815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134428
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