Islet Oxygen Consumption Rate (OCR) Dose Predicts Insulin Independence in Clinical Islet Autotransplantation

BACKGROUND: Reliable in vitro islet quality assessment assays that can be performed routinely, prospectively, and are able to predict clinical transplant outcomes are needed. In this paper we present data on the utility of an assay based on cellular oxygen consumption rate (OCR) in predicting clinic...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Papas, Klearchos K., Bellin, Melena D., Sutherland, David E. R., Suszynski, Thomas M., Kitzmann, Jennifer P., Avgoustiniatos, Efstathios S., Gruessner, Angelika C., Mueller, Kathryn R., Beilman, Gregory J., Balamurugan, Appakalai N., Loganathan, Gopalakrishnan, Colton, Clark K., Koulmanda, Maria, Weir, Gordon C., Wilhelm, Josh J., Qian, Dajun, Niland, Joyce C., Hering, Bernhard J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4530873/
https://ncbi.nlm.nih.gov/pubmed/26258815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134428
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