Islet Oxygen Consumption Rate (OCR) Dose Predicts Insulin Independence in Clinical Islet Autotransplantation

BACKGROUND: Reliable in vitro islet quality assessment assays that can be performed routinely, prospectively, and are able to predict clinical transplant outcomes are needed. In this paper we present data on the utility of an assay based on cellular oxygen consumption rate (OCR) in predicting clinic...

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Veröffentlicht in:PLoS One
Hauptverfasser: Papas, Klearchos K., Bellin, Melena D., Sutherland, David E. R., Suszynski, Thomas M., Kitzmann, Jennifer P., Avgoustiniatos, Efstathios S., Gruessner, Angelika C., Mueller, Kathryn R., Beilman, Gregory J., Balamurugan, Appakalai N., Loganathan, Gopalakrishnan, Colton, Clark K., Koulmanda, Maria, Weir, Gordon C., Wilhelm, Josh J., Qian, Dajun, Niland, Joyce C., Hering, Bernhard J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4530873/
https://ncbi.nlm.nih.gov/pubmed/26258815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134428
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