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Islet oxygen consumption rate (OCR) dose predicts insulin independence for first clinical islet allotransplants

Human islet allotransplant (ITx) for the treatment of type 1 diabetes is in phase III clinical registration trials in the US and standard of care in several other countries. Current islet product release criteria include viability based on cell membrane integrity stains, glucose stimulated insulin r...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kitzmann, JP, O’Gorman, D, Kin, T, Gruessner, AC, Senior, P, Imes, S, Gruessner, RW, Shapiro, AMJ, Papas, KK
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4170186/
https://ncbi.nlm.nih.gov/pubmed/25131089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.transproceed.2014.06.001
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