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Islet oxygen consumption rate (OCR) dose predicts insulin independence for first clinical islet allotransplants

Human islet allotransplant (ITx) for the treatment of type 1 diabetes is in phase III clinical registration trials in the US and standard of care in several other countries. Current islet product release criteria include viability based on cell membrane integrity stains, glucose stimulated insulin r...

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Detalhes bibliográficos
Main Authors: Kitzmann, JP, O’Gorman, D, Kin, T, Gruessner, AC, Senior, P, Imes, S, Gruessner, RW, Shapiro, AMJ, Papas, KK
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4170186/
https://ncbi.nlm.nih.gov/pubmed/25131089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.transproceed.2014.06.001
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