cdc2 phosphorylation is required for its interaction with cyclin.

Activation of the cdc2 protein kinase at different stages of the cell cycle is regulated by post-translational modifications and interactions with cyclins. We show that in vitro translated human cdc2 binds very poorly to A and B cyclins, unless it has been preincubated with a Xenopus egg extract. Th...

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Bibliographic Details
Main Authors: Ducommun, B, Brambilla, P, Félix, M A, Franza, B R, Karsenti, E, Draetta, G
Format: Artigo
Language:Inglês
Published: 1991
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC453057/
https://ncbi.nlm.nih.gov/pubmed/1833185
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