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cdc2 phosphorylation is required for its interaction with cyclin.

Activation of the cdc2 protein kinase at different stages of the cell cycle is regulated by post-translational modifications and interactions with cyclins. We show that in vitro translated human cdc2 binds very poorly to A and B cyclins, unless it has been preincubated with a Xenopus egg extract. Th...

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Autors principals: Ducommun, B, Brambilla, P, Félix, M A, Franza, B R, Karsenti, E, Draetta, G
Format: Artigo
Idioma:Inglês
Publicat: 1991
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC453057/
https://ncbi.nlm.nih.gov/pubmed/1833185
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