A three-dimensional model of the Cdc2 protein kinase: localization of cyclin- and Suc1-binding regions and phosphorylation sites.

The Cdc2 protein kinase requires cyclin binding for activity and also binds to a small protein, Suc1. Charged-to-alanine scanning mutagenesis of Cdc2 was used previously to localize cyclin A- and B- and Suc1-binding sites (B. Ducommun, P. Brambilla, and G. Draetta, Mol. Cell. Biol. 11:6177-6184, 199...

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Main Authors: Marcote, M J, Knighton, D R, Basi, G, Sowadski, J M, Brambilla, P, Draetta, G, Taylor, S S
格式: Artigo
語言:Inglês
出版: 1993
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC360168/
https://ncbi.nlm.nih.gov/pubmed/8336738
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