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A three-dimensional model of the Cdc2 protein kinase: localization of cyclin- and Suc1-binding regions and phosphorylation sites.

The Cdc2 protein kinase requires cyclin binding for activity and also binds to a small protein, Suc1. Charged-to-alanine scanning mutagenesis of Cdc2 was used previously to localize cyclin A- and B- and Suc1-binding sites (B. Ducommun, P. Brambilla, and G. Draetta, Mol. Cell. Biol. 11:6177-6184, 199...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Marcote, M J, Knighton, D R, Basi, G, Sowadski, J M, Brambilla, P, Draetta, G, Taylor, S S
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 1993
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360168/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8336738/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.8.5122-5131.1993
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