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cdc2 phosphorylation is required for its interaction with cyclin.

Activation of the cdc2 protein kinase at different stages of the cell cycle is regulated by post-translational modifications and interactions with cyclins. We show that in vitro translated human cdc2 binds very poorly to A and B cyclins, unless it has been preincubated with a Xenopus egg extract. Th...

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Detalhes bibliográficos
Publicado no:EMBO J
Principais autores: Ducommun, B, Brambilla, P, Félix, M A, Franza, B R, Karsenti, E, Draetta, G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC453057/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1833185/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1991.tb04895.x
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