MicroRNA-9 induces defective trafficking of Nav1.1 and Nav1.2 by targeting Navβ2 protein coding region in rat with chronic brain hypoperfusion

BACKGROUND: Previous studies have demonstrated that the trafficking defects of Nav1.1/Nav1.2 are involved in the dementia pathophysiology. However, the detailed mechanisms are not fully understood. Moreover, whether the impaired miRNAs regulation linked to dementia is a key player in sodium channel...

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Bibliografiske detaljer
Udgivet i:	Mol Neurodegener
Main Authors:	Sun, Li-Hua, Yan, Mei-Ling, Hu, Xue-Ling, Peng, Li-Wei, Che, Hui, Bao, Ya-Nan, Guo, Fei, Liu, Tong, Chen, Xin, Zhang, Rong, Ban, Tao, Wang, Ning, Liu, Huai-Lei, Hou, Xu, Ai, Jing
Format:	Artigo
Sprog:	Inglês
Udgivet:	BioMed Central 2015
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4530481/ https://ncbi.nlm.nih.gov/pubmed/26259688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-015-0032-9
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MicroRNA-9 induces defective trafficking of Nav1.1 and Nav1.2 by targeting Navβ2 protein coding region in rat with chronic brain hypoperfusion

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