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The integrity of the conserved 'WS motif' common to IL-2 and other cytokine receptors is essential for ligand binding and signal transduction.

Recent studies have identified a new family of cytokine receptors, which is primarily characterized by the conservation of periodically interspersed four cysteine residues and the W-S-X-W-S sequence ('WS motif') within the extracellular domain. However, the role of such conserved structure...

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Bibliografske podrobnosti
Main Authors: Miyazaki, T, Maruyama, M, Yamada, G, Hatakeyama, M, Taniguchi, T
Format: Artigo
Jezik:Inglês
Izdano: 1991
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC453042/
https://ncbi.nlm.nih.gov/pubmed/1915291
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