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Functional coupling of the src-family protein tyrosine kinases p59fyn and p53/56lyn with the interleukin 2 receptor: implications for redundancy and pleiotropism in cytokine signal transduction.

The binding of interleukin 2 (IL-2) to the IL-2 receptor (IL-2R) induces a rapid increase in tyrosine phosphorylation of cellular proteins. In a previous study, we have shown that p56lck (lck), a src-family protein tyrosine kinase (src-PTK), physically and functionally associates with the IL-2R beta...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Kobayashi, N, Kono, T, Hatakeyama, M, Minami, Y, Miyazaki, T, Perlmutter, R M, Taniguchi, T
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46474/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8483935/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.9.4201
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