CLC Anion Channel Regulatory Phosphorylation and Conserved Signal Transduction Domains

The signaling mechanisms that regulate CLC anion channels are poorly understood. Caenorhabditis elegans CLH-3b is a member of the CLC-1/2/Ka/Kb channel subfamily. CLH-3b is activated by meiotic cell-cycle progression and cell swelling. Inhibition is brought about by GCK-3 kinase-mediated phosphoryla...

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Detalhes bibliográficos
Main Authors: Miyazaki, Hiroaki, Yamada, Toshiki, Parton, Angela, Morrison, Rebecca, Kim, Sunghoon, Beth, Albert H., Strange, Kevin
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2012
Assuntos:
Channels and Transporters
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475328/
https://ncbi.nlm.nih.gov/pubmed/23083714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.09.001
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