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Differential regulation of a CLC anion channel by SPAK kinase ortholog-mediated multisite phosphorylation

Shrinkage-induced inhibition of the Caenorhabditis elegans cell volume and cell cycle-dependent CLC anion channel CLH-3b occurs by concomitant phosphorylation of S742 and S747, which are located on a 175 amino acid linker domain between cystathionine-β-synthase 1 (CBS1) and CBS2. Phosphorylation is...

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Detalhes bibliográficos
Main Authors: Miyazaki, Hiroaki, Strange, Kevin
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378076/
https://ncbi.nlm.nih.gov/pubmed/22357738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00419.2011
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