KRAS and CREBBP mutations: a relapse-linked malicious liaison in childhood high hyperdiploid acute lymphoblastic leukemia

High hyperdiploidy defines the largest genetic entity of childhood acute lymphoblastic leukemia (ALL). Despite its relatively low recurrence risk, this subgroup generates a high proportion of relapses. The cause and origin of these relapses remains obscure. We therefore explored the mutational lands...

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Dades bibliogràfiques
Publicat a:Leukemia
Autors principals: Malinowska-Ozdowy, K, Frech, C, Schönegger, A, Eckert, C, Cazzaniga, G, Stanulla, M, zur Stadt, U, Mecklenbräuker, A, Schuster, M, Kneidinger, D, von Stackelberg, A, Locatelli, F, Schrappe, M, Horstmann, M A, Attarbaschi, A, Bock, C, Mann, G, Haas, O A, Panzer-Grümayer, R
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
Matèries:
Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4530204/
https://ncbi.nlm.nih.gov/pubmed/25917266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2015.107
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