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Genomic and transcriptional landscape of P2RY8-CRLF2-positive childhood acute lymphoblastic leukemia

Children with P2RY8-CRLF2-positive acute lymphoblastic leukemia have an increased relapse risk. Their mutational and transcriptional landscape, as well as the respective patterns at relapse remain largely elusive. We, therefore, performed an integrated analysis of whole-exome and RNA sequencing in 4...

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Detalhes bibliográficos
Publicado no:Leukemia
Main Authors: Vesely, C, Frech, C, Eckert, C, Cario, G, Mecklenbräuker, A, zur Stadt, U, Nebral, K, Kraler, F, Fischer, S, Attarbaschi, A, Schuster, M, Bock, C, Cavé, H, von Stackelberg, A, Schrappe, M, Horstmann, M A, Mann, G, Haas, O A, Panzer-Grümayer, R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5508072/
https://ncbi.nlm.nih.gov/pubmed/27899802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2016.365
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