Podocyte Injury–Driven Lipid Peroxidation Accelerates the Infiltration of Glomerular Foam Cells in Focal Segmental Glomerulosclerosis

Intracapillary foam cell infiltration with podocyte alterations is a characteristic pathology of focal segmental glomerulosclerosis (FSGS). We investigated the possible role of podocyte injury in glomerular macrophage and foam cell infiltration in a podocyte-selective injury model (NEP25 mice) and h...

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Udgivet i:Am J Pathol
Main Authors: Hara, Satoshi, Kobayashi, Namiko, Sakamoto, Kazuo, Ueno, Toshiharu, Manabe, Shun, Takashima, Yasutoshi, Hamada, Juri, Pastan, Ira, Fukamizu, Akiyoshi, Matsusaka, Taiji, Nagata, Michio
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2015
Fag:
Regular Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4530130/
https://ncbi.nlm.nih.gov/pubmed/26072030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2015.04.007
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