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Glomerular sclerosis is prevented during urinary tract obstruction due to podocyte protection

Urine outflow obstruction activates a variety of profibrotic factors, including the intrarenal renin-angiotensin system. However, the obstruction also nullifies the transmural hydraulic pressure difference across the glomerular capillary wall, an established inducer of glomerulosclerosis. In the pre...

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Main Authors: Matsusaka, Taiji, Kobayashi, Kazuto, Kon, Valentina, Pastan, Ira, Fogo, Agnes B., Ichikawa, Iekuni
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064125/
https://ncbi.nlm.nih.gov/pubmed/21177778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00570.2010
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