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Glomerular sclerosis is prevented during urinary tract obstruction due to podocyte protection
Urine outflow obstruction activates a variety of profibrotic factors, including the intrarenal renin-angiotensin system. However, the obstruction also nullifies the transmural hydraulic pressure difference across the glomerular capillary wall, an established inducer of glomerulosclerosis. In the pre...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Physiological Society
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3064125/ https://ncbi.nlm.nih.gov/pubmed/21177778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00570.2010 |
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