Possible role of complement factor H in podocytes in clearing glomerular subendothelial immune complex deposits

Podocytes are known to express various complement factors including complement factor H (CFH) and to promote the removal of both subendothelial and subepithelial immune complex (IC) deposits. Using podocyte-selective injury model NEP25 mice and an IgG3-producing hybridoma clone 2B11.3 established by...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Zoshima, Takeshi, Hara, Satoshi, Yamagishi, Masakazu, Pastan, Ira, Matsusaka, Taiji, Kawano, Mitsuhiro, Nagata, Michio
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6536504/
https://ncbi.nlm.nih.gov/pubmed/31133737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44380-3
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