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Antigenic stimulation of Kv1.3-deficient helper T cells gives rise to a population of Foxp3-independent T cells with suppressive properties

Multiple sclerosis (MS) is an immune-mediated demyelinating disease of the central nervous system that has been linked with defects in regulatory T cell function. Therefore, strategies to selectively target pathogenic cells via enhanced regulatory T cell activity may provide therapeutic benefit. Kv1...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Grishkan, Inna V., Tosi, Dominique M., Bowman, Melissa D., Harary, Maya, Calabresi, Peter A., Gocke, Anne R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4530110/
https://ncbi.nlm.nih.gov/pubmed/26150529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1403024
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