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Effects of Physiological and Synthetic IAP Antagonism on c-IAP-Dependent Signaling

Cellular inhibitor of apoptosis proteins 1 and 2 (c-IAP1/2) play central roles in signal transduction mediated by numerous receptors that participate in inflammatory and immune responses. In certain pathways, such as activation of NF-κB, their degradation is a major regulatory event and is physiolog...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncogene
Prif Awduron: Kocab, Andrew J., Veloso, Artur, Paulsen, Michelle T., Ljungman, Mats, Duckett, Colin S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4530109/
https://ncbi.nlm.nih.gov/pubmed/25659587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.3
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