IAP antagonization promotes inflammatory destruction of vascular endothelium

In this study, we show for the first time that the therapeutic antagonization of inhibitor of apoptosis proteins (IAPs) inhibits B16 melanoma growth by disrupting tumor vasculature. Specifically, the treatment of mice bearing B16 melanoma with an IAP antagonist compound A (Comp A) inhibits tumor gro...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:EMBO Rep
मुख्य लेखकों: Witt, Axel, Seeger, Jens M, Coutelle, Oliver, Zigrino, Paola, Broxtermann, Pia, Andree, Maria, Brinkmann, Kerstin, Jüngst, Christian, Schauss, Astrid C, Schüll, Stephan, Wohlleber, Dirk, Knolle, Percy A, Krönke, Martin, Mauch, Cornelia, Kashkar, Hamid
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BlackWell Publishing Ltd 2015
विषय:
Scientific Reports
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4467856/
https://ncbi.nlm.nih.gov/pubmed/25825408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201439616
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