Cytochrome c oxidase deficiency accelerates mitochondrial apoptosis by activating ceramide synthase 6

Although numerous pathogenic changes within the mitochondrial respiratory chain (RC) have been associated with an elevated occurrence of apoptosis within the affected tissues, the mechanistic insight into how mitochondrial dysfunction initiates apoptotic cell death is still unknown. In this study, w...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cell Death Dis
Päätekijät: Schüll, S, Günther, S D, Brodesser, S, Seeger, J M, Tosetti, B, Wiegmann, K, Pongratz, C, Diaz, F, Witt, A, Andree, M, Brinkmann, K, Krönke, M, Wiesner, R J, Kashkar, H
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2015
Aiheet:
Original Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4385940/
https://ncbi.nlm.nih.gov/pubmed/25766330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.62
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