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A tissue‐specific screen of ceramide expression in aged mice identifies ceramide synthase‐1 and ceramide synthase‐5 as potential regulators of fiber size and strength in skeletal muscle

Loss of skeletal muscle mass is one of the most widespread and deleterious processes in aging humans. However, the mechanistic metabolic principles remain poorly understood. In the framework of a multi‐organ investigation of age‐associated changes of ceramide species, a unique and distinctive change...

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Bibliographic Details
Published in:Aging Cell
Main Authors: Tosetti, Bettina, Brodesser, Susanne, Brunn, Anna, Deckert, Martina, Blüher, Matthias, Doehner, Wolfram, Anker, Stefan D., Wenzel, Daniela, Fleischmann, Bernd, Pongratz, Carola, Peters, Franziska, Utermöhlen, Olaf, Krönke, Martin
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6974707/
https://ncbi.nlm.nih.gov/pubmed/31692231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13049
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