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Cytochrome c oxidase deficiency accelerates mitochondrial apoptosis by activating ceramide synthase 6
Although numerous pathogenic changes within the mitochondrial respiratory chain (RC) have been associated with an elevated occurrence of apoptosis within the affected tissues, the mechanistic insight into how mitochondrial dysfunction initiates apoptotic cell death is still unknown. In this study, w...
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| Udgivet i: | Cell Death Dis |
|---|---|
| Main Authors: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4385940/ https://ncbi.nlm.nih.gov/pubmed/25766330 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.62 |
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