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Two distinct signalling cascades target the NF-κB regulatory factor c-IAP1 for degradation
c-IAP1 (cellular inhibitor of apoptosis 1) has recently emerged as a negative regulator of the non-canonical NF-κB (nuclear factor κB) signalling cascade. Whereas synthetic IAP inhibitors have been shown to trigger the autoubiquitination and degradation of c-IAP1, less is known about the physiologic...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Portland Press Ltd.
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2677214/ https://ncbi.nlm.nih.gov/pubmed/19243308 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20082140 |
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