Llwytho...

CASPASES AND IAPS: A DANCE OF DEATH ENSURES CELL SURVIVAL

In this issue of Molecular Cell, Ditzel et al show that DIAP1 polyubiquitinates DRONC, DCP-1 and drICE, leading to their non-degradative inactivation. Surprisingly, activation of DIAP1 requires caspase-mediated cleavage, revealing an elegant feedback mechanism by which caspases regulate their own fa...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Galbán, Stefanie, Brady, Graham F., Duckett, Colin S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2744384/
https://ncbi.nlm.nih.gov/pubmed/19026777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.11.005
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