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Reawakening the cellular death program in neoplasia through the therapeutic blockade of IAP function

Recent studies have shown that members of the inhibitor of apoptosis (IAP) protein family are highly expressed in several classes of cancer. The primary implication of these findings is that the elevated expression of IAPs is not coincidental but actually participates in oncogenesis by helping to al...

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Detalhes bibliográficos
Main Authors: Wright, Casey W., Duckett, Colin S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1236691/
https://ncbi.nlm.nih.gov/pubmed/16200201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI26251
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