CYTOPROTECTIVE EFFECTS OF IAPS REVEALED BY A SMALL MOLECULE ANTAGONIST

Deregulated expression of members of the Inhibitor of Apoptosis (IAP) family has been found in a wide variety of neoplastic cells, and synthetic IAP antagonists represent a promising novel class of chemotherapeutic agents. Early work focused on the ability of these compounds to block the caspase inh...

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Bibliografiske detaljer
Main Authors: Galbán, Stefanie, Hwang, Clara, Rumble, Julie M., Oetjen, Karolyn A., Wright, Casey W., Boudreault, Alain, Durkin, Jon, Gillard, John W., Jaquith, James B., Morris, Stephen J., Duckett, Colin S.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2674510/
https://ncbi.nlm.nih.gov/pubmed/18851715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20081677
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