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Positive Allosteric Modulators of Metabotropic Glutamate 2 Receptors in Schizophrenia Treatment

The last two decades have witnessed a rise in the “NMDA receptor hypofunction” hypothesis for schizophrenia, a devastating disorder that affects around 1% of the population worldwide. A variety of presynaptic, postsynaptic and regulatory proteins involved in glutamatergic signaling have thus been pr...

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Publicado en:Trends Neurosci
Autores principales: Ellaithy, Amr, Younkin, Jason, Gonzalez-Maeso, Javier, Logothetis, Diomedes E.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4530036/
https://ncbi.nlm.nih.gov/pubmed/26148747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tins.2015.06.002
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