The novel metabotropic glutamate receptor 2 positive allosteric modulator, AZD8529, decreases nicotine self-administration and relapse in squirrel monkeys

BACKGROUND: Based on rodent studies, Group II metabotropic glutamate receptors (mGluR2 & 3) were suggested as targets for addiction treatment. However, LY379268 and other Group II agonists do not discriminate between the mainly presynaptic inhibitory mGluR2 (the proposed treatment target) and mG...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Biol Psychiatry
Autori principali: Justinova, Zuzana, Panlilio, Leigh V., Secci, Maria E., Redhi, Godfrey H., Schindler, Charles W., Cross, Alan J., Mrzljak, Ladislav, Medd, Amy, Shaham, Yavin, Goldberg, Steven R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4529372/
https://ncbi.nlm.nih.gov/pubmed/25802079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2015.01.014
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi