Optimal treatment scheduling of ionizing radiation and sunitinib improves the antitumor activity and allows dose reduction

The combination of radiotherapy with sunitinib is clinically hampered by rare but severe side effects and varying results with respect to clinical benefit. We studied different scheduling regimes and dose reduction in sunitinib and radiotherapy in preclinical tumor models to improve potential outcom...

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Bibliografske podrobnosti
izdano v:Cancer Med
Main Authors: Kleibeuker, Esther A, ten Hooven, Matthijs A, Castricum, Kitty C, Honeywell, Richard, Griffioen, Arjan W, Verheul, Henk M, Slotman, Ben J, Thijssen, Victor L
Format: Artigo
Jezik:Inglês
Izdano: John Wiley & Sons, Ltd 2015
Teme:
Clinical Cancer Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4529339/
https://ncbi.nlm.nih.gov/pubmed/25828633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.441
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