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Optimal treatment scheduling of ionizing radiation and sunitinib improves the antitumor activity and allows dose reduction

The combination of radiotherapy with sunitinib is clinically hampered by rare but severe side effects and varying results with respect to clinical benefit. We studied different scheduling regimes and dose reduction in sunitinib and radiotherapy in preclinical tumor models to improve potential outcom...

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Detalhes bibliográficos
Publicado no:Cancer Med
Main Authors: Kleibeuker, Esther A, ten Hooven, Matthijs A, Castricum, Kitty C, Honeywell, Richard, Griffioen, Arjan W, Verheul, Henk M, Slotman, Ben J, Thijssen, Victor L
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4529339/
https://ncbi.nlm.nih.gov/pubmed/25828633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.441
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