Low dose angiostatic treatment counteracts radiotherapy-induced tumor perfusion and enhances the anti-tumor effect

The extent of tumor oxygenation is an important factor contributing to the efficacy of radiation therapy (RTx). Interestingly, several preclinical studies have shown benefit of combining RTx with drugs that inhibit tumor blood vessel growth, i.e. angiostatic therapy. Recent findings show that proper...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Kleibeuker, Esther A., Fokas, Emmanouil, Allen, Philip D., Kersemans, Veerle, Griffioen, Arjan W., Beech, John, Im, Jaehong H., Smart, Sean C., Castricum, Kitty C., van den Berg, Jaap, Schulkens, Iris A., Hill, Sally A., Harris, Adrian L., Slotman, Ben J., Verheul, Henk M., Muschel, Ruth J., Thijssen, Victor L.
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2016
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363534/
https://ncbi.nlm.nih.gov/pubmed/27780936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12814
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