Low dose angiostatic treatment counteracts radiotherapy-induced tumor perfusion and enhances the anti-tumor effect

The extent of tumor oxygenation is an important factor contributing to the efficacy of radiation therapy (RTx). Interestingly, several preclinical studies have shown benefit of combining RTx with drugs that inhibit tumor blood vessel growth, i.e. angiostatic therapy. Recent findings show that proper...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Kleibeuker, Esther A., Fokas, Emmanouil, Allen, Philip D., Kersemans, Veerle, Griffioen, Arjan W., Beech, John, Im, Jaehong H., Smart, Sean C., Castricum, Kitty C., van den Berg, Jaap, Schulkens, Iris A., Hill, Sally A., Harris, Adrian L., Slotman, Ben J., Verheul, Henk M., Muschel, Ruth J., Thijssen, Victor L.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363534/
https://ncbi.nlm.nih.gov/pubmed/27780936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12814
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