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High-Throughput Assay Development for Cystine-Glutamate Antiporter (x(c) (-)) Highlights Faster Cystine Uptake than Glutamate Release in Glioma Cells
The cystine-glutamate antiporter (system x(c) (-)) is a Na(+)-independent amino acid transporter that exchanges extracellular cystine for intracellular glutamate. It is thought to play a critical role in cellular redox processes through regulation of intracellular glutathione synthesis via cystine u...
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| Publicat a: | PLoS One |
|---|---|
| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4529246/ https://ncbi.nlm.nih.gov/pubmed/26252954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0127785 |
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