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Increased expression of cystine/glutamate antiporter in multiple sclerosis

BACKGROUND: Glutamate excitotoxicity contributes to oligodendrocyte and tissue damage in multiple sclerosis (MS). Intriguingly, glutamate level in plasma and cerebrospinal fluid of MS patients is elevated, a feature which may be related to the pathophysiology of this disease. In addition to glutamat...

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Détails bibliographiques
Auteurs principaux: Pampliega, Olatz, Domercq, María, Soria, Federico N, Villoslada, Pablo, Rodríguez-Antigüedad, Alfredo, Matute, Carlos
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3117706/
https://ncbi.nlm.nih.gov/pubmed/21639880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-8-63
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