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Dentin phosphophoryn in the matrix activates AKT and mTOR signaling pathway to promote preodontoblast survival and differentiation

Dentin phosphophoryn (DPP) is an extracellular matrix protein synthesized by odontoblasts. It is highly acidic and the phosphorylated protein possesses a strong affinity for calcium ions. Therefore, DPP in the extracellular matrix can promote hydroxyapatite nucleation and can regulate the size of th...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Eapen, Asha, George, Anne
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4528161/
https://ncbi.nlm.nih.gov/pubmed/26300786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2015.00221
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