The p63 Gene Is Regulated by Grainyhead-like 2 (GRHL2) through Reciprocal Feedback and Determines the Epithelial Phenotype in Human Keratinocytes

In this study, we investigated the effects of p63 modulation in epithelial plasticity in human keratinocytes. The p63 isoforms ΔNp63α, ΔNp63β, and ΔNp63γ were ectopically expressed in normal human epidermal keratinocytes (NHEKs). The epithelial or mesenchymal state was determined by morphological ch...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Mehrazarin, Shebli, Chen, Wei, Oh, Ju-Eun, Liu, Zi X., Kang, Kyung L., Yi, Jin K., Kim, Reuben H., Shin, Ki-Hyuk, Park, No-Hee, Kang, Mo K.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2015
Konular:
Cell Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4528158/
https://ncbi.nlm.nih.gov/pubmed/26085095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.659144
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