Grainyhead-like 2 (GRHL2) inhibits keratinocyte differentiation through epigenetic mechanism

We recently identified Grainyhead-like 2 (GRHL2), a mammalian homolog of Grainyhead in Drosophila, to be a novel transcription factor that regulates hTERT gene expression and enhances proliferation of normal human epidermal keratinocytes (NHEK). In the current study, we show that GRHL2 impairs kerat...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Chen, W, Xiao Liu, Z, Oh, J-E, Shin, K-H, Kim, R H, Jiang, M, Park, N-H, Kang, M K
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2012
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3542624/
https://ncbi.nlm.nih.gov/pubmed/23254293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2012.190
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