Dual Roles of the Transcription Factor Grainyhead-like 2 (GRHL2) in Breast Cancer

Using a retrovirus-mediated cDNA expression cloning approach, we identified the grainyhead-like 2 (GRHL2) transcription factor as novel protooncogene. Overexpression of GRHL2 in NIH3T3 cells induced striking morphological changes, an increase in cell proliferation, anchorage-independent growth, and...

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Detalhes bibliográficos
Main Authors: Werner, Stefan, Frey, Sabrina, Riethdorf, Sabine, Schulze, Christian, Alawi, Malik, Kling, Lea, Vafaizadeh, Vida, Sauter, Guido, Terracciano, Luigi, Schumacher, Udo, Pantel, Klaus, Assmann, Volker
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3743475/
https://ncbi.nlm.nih.gov/pubmed/23814079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.456293
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