Direct Generation of Triketide Stereopolyads via Merged Redox-Construction Events: Total Synthesis of (+)-Zincophorin Methyl Ester

[Image: see text] (+)-Zincophorin methyl ester is prepared in 13 steps (longest linear sequence). A bidirectional redox-triggered double anti-crotylation of 2-methyl-1,3-propane diol directly assembles the triketide stereopolyad spanning C4-C12, significantly enhancing step-economy and enabling cons...

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Bibliographic Details
Published in:J Am Chem Soc
Main Authors: Kasun, Zachary A., Gao, Xin, Lipinski, Radoslaw M., Krische, Michael J.
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4527649/
https://ncbi.nlm.nih.gov/pubmed/26167950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b05296
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