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Coordinated Evolution of Influenza A Surface Proteins

The surface proteins hemagglutinin (HA) and neuraminidase (NA) of human influenza A virus evolve under selection pressures to escape adaptive immune responses and antiviral drug treatments. In addition to these external selection pressures, some mutations in HA are known to affect the adaptive lands...

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Publicado en:PLoS Genet
Main Authors: Neverov, Alexey D., Kryazhimskiy, Sergey, Plotkin, Joshua B., Bazykin, Georgii A.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4527594/
https://ncbi.nlm.nih.gov/pubmed/26247472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005404
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