Directionality in the evolution of influenza A haemagglutinin

The evolution of haemagglutinin (HA), an important influenza virus antigen, has been the subject of intensive research for more than two decades. Many characteristics of HA's sequence evolution are captured by standard Markov chain substitution models. Such models assign equal fitness to all ac...

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Detaylı Bibliyografya
Asıl Yazarlar: Kryazhimskiy, Sergey, Bazykin, Georgii A, Plotkin, Joshua, Dushoff, Jonathan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Royal Society 2008
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2603193/
https://ncbi.nlm.nih.gov/pubmed/18647721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2008.0521
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